Ciprofloxacin is a synthetic chemotherapeutic antibiotic that kills bacteria by interfering with that cause DNA to rewind after being copied. When this occurs, it stops DNA and protein synthesis. The drug is a second generation fluoroquinolone antibacterial and is widely marketed in more than hundred brand names worldwide including proquin, cipro XL, baycip, ciloxan, ciflox, cipro xr, prociflor and ciprex. Having being patented in the year 1983 and approved by the U.S food and drug administration, it has been widely used across the globe for human and veterinary uses. Ciprofloxacin is also used off label in some countries where it has not been FDA -approved.
There are many Ciprofloxacin Uses which include the treatment of different infections in humans. People suffering from bone and joint infection can be treated effectively using the drug. Endocarditis, gastroenterities, malignant otitis externa can also be treated using Ciprofloxacin. In some cases, Ciprofloxacin has been widely used on patients suffering from respiratory tract infections and it works efficiently. Patients suffering from urinary tract infections are also treated using the drug although it is not always advisable as a first line antibiotic for the infections. Ciprofloxacin is also widely used by medics in treatment of cellulitis, anthrax, chancroid, prostatitis among other diseases.
Similarly, patients suffering from uncomplicated cervical and urethra gonorrhea are treated using the drug, especially in parts of the globe with no bacterial resistance. In the USA, CANADA, SCOTLAND and ASIAN countries, the drug is not very effective in treatment of urethra gonorrhea because of bacterial resistance. Additionally, Ciprofloxacin is effective in treatment of infectious diarrhea, skin and skin structure infections, typhoid fever caused by salmonella typhi. Acute sinusitis can also be treated using the drug. For the above diseases, Ciprofloxacin is used with no other drug combination. However, the drug can be used in treatment of other diseases when used in combination with other drugs such as metronidazole and peperacilllin.
Patients suffering from complicated intra- abdominal infections can be treated using Ciprofloxacin in combination with metronidazole. On the other hand, it has been widely used in combination with piperacillin for empirical therapy in patients suffering from febrile neutropenic. Pediatric use of Ciprofloxacin however is highly restricted in some countries because of drug reactions. In young children, the drug can be used orally to treat lower respiratory infections and cystic fibrosis especially in the UK. However, it has not been US FDA approved because of risk exposure to permanent injury of musculoskeletal system.
In pediatric population, Ciprofloxacin is very effective in the treatment of inhalation anthrax. Other Ciprofloxacin Uses include treatment of specific community acquired pneumonia (CAP) infections when combined with beta-lactam drug, chronic bronchitis, head cold, viral respiratory infections, sore throats, some sexually transmitted diseases and chest infections.
Despite the enormous uses of the drug in medicine, it cannot be administered to patients with a history of hypersensitivity due to drug reactions which may aggregate the situation. Drug use in Nursing mothers and pregnant women is highly restricted because the drug can be distributed to fetal tissues which can cause abortion or birth defects and certain syndromes when passed through breast milk.